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The changes make the peptide more resistant to enzymatic degradation, which enables it to be used in research studies over a long duration

In the STEP 1 trial, semaglutide produced average weight loss of approximately 15% over 68 weeks, while the SURMOUNT-1 trial showed tirzepatide achieved 15-21% weight loss over 72 weeks

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In several reports, patients were instructed to use a U-100 (1 milliliter) insulin syringe to draw small doses, such as a 5-unit (0.05 milliliter) dose, from a multiple-dose vial

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A glucagon-like peptide-1 (GLP-1) receptor agonist, it mimics the body's natural GLP-1 hormone to help regulate blood sugar levels