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Signaling functions of reactive oxygen species

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For example, engineered EcN is designed to efficiently metabolize intestinal ammonia and convert it into beneficial amino acids such as L-arginine, thereby systematically reducing blood ammonia levels [163]

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For example, thiazolidinediones, which inhibit ACSL4, can cause cardiac toxicity with prolonged use ( Statements Author contributions YZ: Conceptualization, Data curation, Formal Analysis, Writingoriginal draft