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The routine cell proliferation resulted in increased percentages of live cells in both treated and untreated groups of day 3 and day 5 compared to the control group (i.e., 24 h cell culture with no treatment)

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The investigators reported partial restoration of the circadian melatonin rhythm in elderly subjects following the epithalamin course, with measurable but incomplete return toward younger-adult patterns of nocturnal melatonin secretion [2]