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If you have neurological symptoms (pins and needles, numbness, balance issues), severe fatigue, unexplained weight loss, chest pain, breathlessness, or symptoms that are worsening, you should seek medical assessment promptly.

At present, neither NICE nor the MHRA has issued guidance on the combined use of retatrutide and sermorelin, largely because retatrutide remains unlicensed in the UK

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As this technology becomes more widespread, its integration into standard medical protocols appears inevitable