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Patients often report symptoms like nausea and diarrhea, with emerging evidence pointing to potential risks of more severe gastrointestinal complications

That led to approval for using the medications in people with obesity

Diabetes Care 27 , 23482355 (2004)

But the user experience differs in ways that matter for daily compliance

If you test positive, isolate from others, monitor your symptoms and contact your primary care provider to discuss treatment options

In July 2009, they published a paper in Nature Chemical Biology, reporting for the first time that dual agonists targeting GLP-1R and glucagon receptor (GCGR) had a better weight loss effect