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Melanotan II ist eine verkrzte zyklische Version des gleichen Peptids mit der Aminosurenfolge Leu- Asp-His-Phe-Arg-Trp-Lys.Melanotan I and Melanotan II are known as synthetic analogues of the melanocyte-stimulating hormone

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For EXSCEL, while the point estimate for MACE reduction was favourable (HR 0.91), it did not reach statistical significance, a result potentially confounded by high rates of treatment discontinuation and the inclusion of a relatively lower-risk population [17,65]

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The in vivo study showed a significant reduction in TMAO levels in C57BL/6(FMO3 +/+ ) strain WT mouse models and in TMA levels in C57BL/6 -Fmo3em1Smoc (KO) mouse models

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