and J.T.-D
Simultaneously, the synthesis and recycling of GSH are critical for maintaining intracellular antioxidant capacity, and the depletion of GPX4 leads to the disruption of this cycle 12
GSSG was higher and GSH:GSSG lower in asthmatic compared with HC BAL fluid, while intracellular GSH was lower in asthma
ICD-10 = International classification of diseases, version 10, CPT = current procedural terminology, ATC = anatomical therapeutic chemical classification system, TNX = TriNetX curated codes, RxNorm = US normalized drug names
Analysis of single-cell RNA sequencing Single-cell RNA sequencing (scRNA-seq) data (HRA000425) were downloaded from Genome Sequence Archive (SRA)-Human databases in China National Center for Bioinformation 16 , converted into FASTQ format using fasterq-dump software (sratoolkit 3.0.2, NCBI, NIH, Bethesda, MD, USA), converted into a matrix data file using Cell Ranger software version 3.0.2 (10xGenomics, Pleasanton, CA, USA), converted into Seurat objects using Seurat 5.0.1 software (Satija lab, Lower Manhattan, New York, NY, USA), and plotted for t -distributed stochastic neighbor embedding ( t -SNE) visualization
Bikle DD, Vitamin D (2014) metabolism, mechanism of action, and clinical applications
