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A downstream mediator in the growth repression limb of the jasmonate pathway

Second, for translational tool development, multifunctional delivery systems should be optimized

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In addition, metabolic dysfunctions, such as insulin resistance, dyslipidemia, and cardiovascular disease are all associated with hepatic steatosis, and seem to be more related to hepatic fat accumulation and NAFLD than obesity status per se [2, 9, 10]

Lastly, the observational design, lack of standardized outcome measures, small sample size and heterogeneity of responses to semaglutide treatment, likely due to the complex nature of obesity in PWS, reduces the generalizability of the findings to a wider population

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