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Understanding irAEs With the advent of immunotherapy, oncologists and cancer researchers accustomed to the familiar, decades-old set of toxic side effects from chemotherapies and radiotherapy are being challenged with understanding and defining a new set of short-term and long-term side effects, referred to as irAEs, to provide timely and effective remedies to cancer patients experiencing them

Two nearby acidic residues (Glu205/Glu206) play important roles in positioning the substrate for catalysis

Type II diabetes is also listed as a presumptive condition by the VA if you were exposed to Agent Orange while serving during the Vietnam War

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