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Observational studies indicate fewer alcohol-related healthcare events among GLP-1RA users
Wei R, Christakos S
This gives it great potential to help in the treatment and prevention of heart disease and heart failure 30 , specifically when combined with other treatments and lifestyle changes
79 Furthermore, activation of the nuclear factor E2-related factor 2 (Nrf2)/Kelch-like ECH-associated protein 1(KEAP-1)-GPX4 pathway also exhibits excellent antiferroptosis effects by inhibiting lipid peroxidation by upregulation of GPX4 and SLC7A11 transcription and increases in NADPH and GSH levels
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