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Future work will need to address these gaps to fully elucidate the therapeutic potential and mechanism of action of SR4

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Klos C, Koob M, Kramer C, Dekant W (1992) p-aminophenol nephrotoxicity: biosynthesis of toxic glutathione conjugates

90% of participants Achieved A1c of less than 7% Lost up to 10.5kg (23.10lbs) Improvements seen in 40 weeks Side effects: diarrhea and nausea The dose used in these trials ranged from 5 to 15 mg