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an anticancer drug, when Irinotecan and GRA16 were administered together, they synergistically promoted the anticancerous effect of Irinotecan by inducing a cell cycle arrest and inhibiting NF-B

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Taking large amounts of vitamin C can also prevent glutathione levels from dropping because vitamin C helps the dermal cells to produce glutathione

[DOI] [PMC free article] [PubMed] [Google Scholar] 2.Shorey S., Ng E.D., Wong C.H.J

Additionally, GCGR activation may indirectly influence fibrogenesis by modulating the hepatic metabolic milieu, reducing lipotoxicity and oxidative stress that serve as upstream triggers for fibrotic pathways (39, 47)