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Several in vitro and in vivo experimental models have highlighted a decreased cholesterol synthesis in deficient G6PD cells or animals [12, 14, 49] as well as a concomitant increase in lipid peroxidation, which suggests that the impairment of the antioxidant defense prevails over the cholesterol-lowering effect [94]

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doi: 10.1016/j.neuro.2023.03.004 70 HanX.LiQ.LanX.el-MuftiL.RenH.WangJ

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