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Research highlighted by Imperial College London shows mixed but intriguing results: while some trials have not met primary endpoints, others demonstrate signals such as reduced brain shrinkage and slower cognitive decline

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These results suggest that exendin-4-induced suppression may be mediated by a distinct G s /cAMP-PKA/IP 3 /Ca 2+ /CaM/CaMKII signaling pathway, following the activation of GLP-1Rs

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The present study identifies an important function of the intestinal protease TMPRSS2 in fine-tuning postprandial metabolic responses

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