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However, it is dangerous to use these supplements indiscriminately

However, pharmacokinetic data indicate that a 0.03 mg dose of LIR reaches its maximum concentration (T-max) approximately 8 h after administration, with behavioral effects detectable by 6 h (Douton et al., 2022a)

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Seizure disorders: ALCAR has been associated with increased number or severity of seizures, particularly at high doses [1][5]

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A multicenter RCT, the PIVENS 262 trial, randomized 247 nondiabetic patients treated with MASH into the pioglitazone, vitamin E, and placebo groups for 96 weeks