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It works systemically to promote cellular migration and tissue repair

*Correspondence: Nils Wierup, [email protected] Specialty section: This article was submitted to Neuroendocrine Science, a section of the journal Frontiers in Endocrinology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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Initial losses often include water weight and reduced inflammation as dietary patterns improve

Metformin inhibits methylglyoxal-induced retinal pigment epithelial cell death and retinopathy via AMPK-Dependent mechanisms: reversing mitochondrial dysfunction and upregulating glyoxalase 1