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10.1179/1476830513Y.0000000071 Nutr
128-channel AEPs were recorded during a frequency oddball discrimination task at protocol onset, at the point of cross-over, and at the end of the study
*Correspondence: Ana Maria Castejon [email protected] This article was submitted to Child and Adolescent Psychiatry, a section of the journal Frontiers in Psychiatry Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers
GCL, heterodimer made up of the heavy sub unit (73 kDa) has the catalytic activity (GCLC), and is the site of GSH feed back inhibition The light (30 kDa) or modifier (GCLM) sub unit, alter, or regulate the activity of the holoenzyme Glutamate cysteine ligase (GCL) L-glutamate + L-cysteine + ATP -L-glutamyl-L-cysteine + ADP + Pi GCL is regultate physiologically by : Feed back competitive inhibition by GSH The availability of its precurser, L-cysteine
The dismutation of O 2 . results in the formation of hydrogen peroxide (H 2 O 2 ), which can lead to elevated levels of other potentially harmful reactive oxygen and nitrogen species (ROS, RNS) 2