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The effects appeared gradually over the multi-week treatment period

Dec 2016;109:142-148

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doi: 10.3389/fnut.2021.652767 73 Azarcoya-BarreraJLewisEDFieldCJGorukSMakarowskiAPouliotYet al

Start your intake Start Low and Increase Slowly: The Dose Escalation Strategy The most effective way to reduce GLP-1 side effects is following a gradual dose escalation protocol