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Uhler ML, Marks JW, Voigt BJ, Judd HL

The lapse went largely unnoticed until it was recently highlighted by Derek Lowe in Science, where he described it as an eyebrow-raising moment for a company with so much at stake

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The decrease in HGF-dependent MDCK proliferation below control levels for some compounds is not surprising since the experiment was earned in 2% serum, which likely contains some level of HGF

If fasting glucose trends upward or HbA1c increases, this signals developing insulin resistance