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Diagnosis involves serum B12 measurement (levels below 148 pmol/L indicate deficiency

Their seemingly miraculous properties have been praised by tech CEOs, podcaster Joe Rogan, and celebrities such as Gwyneth Paltrow, Jennifer Aniston, and Kim Kardashian, who says her daily regimen changed my life. But many doctors are alarmed by a craze that has thousands of people injecting themselves with substances of dubious origin and whose long-term effects are unknown

Vomiting, anorexia, headache, irritability, tremors, and palpitations, can be overdose syndromes (33-34)

3 Data Sources : A PubMed search was completed in Clinical Queries using the key terms vitamin B 12 , cobalamin, deficiency, and treatment

MiR-93 induces HCC cell proliferation and invasion by activating c-Met/PI3K/Akt signaling pathways and targeting PDCD4 and TIMP2 (Ohta et al., 2015

B12 shots have been shown to boost mood, increase energy, and provide an improved sense of well-being