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There are two main forms: CJC 1295 with DAC (Drug Affinity Complex): A longer acting version that stays active for up to a week, reducing injection frequency

However, if clearance fails, these UMAs undergo bipolar growth to forge standard full-sized needle-like monosodium urate crystals (nsMSUs) which directly induce neutrophils, resulting in the formation of NETs (84)

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Means were compared using one-way ANOVA followed by a Dunnett multiple comparisons to analyze differences in the area under the curve from CLS assays and exponential growth

Translating nanomaterials from laboratory to clinic: barriers ahead