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Ageing Dev

Randomized phase III clinical trial of five different arms of treatment in 332 patients with cancer cachexia

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It is proposed to work by binding GHRH receptors on pituitary somatotroph cells, prompting the pituitary to synthesize and release its own growth hormone in a pulsatile pattern, with the body's somatostatin feedback loop still intact so the effect is self-limiting rather than a constant hormone flood