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Oxytocin: Widely studied intranasally in neuroscience research

L-2-oxothiazolidine-4-carboxylic acid (OTC) treatment attenuated plasma and tissue P-selectin levels, suggesting that the upregulation of P-selectin in hyperhomocysteinemic mice is also regulated by redox mechanisms [61]

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Hess and colleagues have recently demonstrated that both mice with TNF--mediated arthritis and humans with RA show enhanced brain activity in the centers involved in pain perception and the control of emotions [77]