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Some people may also experience adverse effects like mild diarrhea, itching, or a swelling sensation in the body

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AOD-9604's pivotal Phase 2b trial failed its primary endpoint: 536 participants, 24 weeks, no statistically significant fat loss versus placebo

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The concept works like this: by presenting the body's own peptide epitopes, the fragments of self-proteins that T cells recognize, in a tolerogenic context, researchers can selectively delete or suppress the specific T cell clones responsible for autoimmune attack