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Similar content being viewed by others Introduction Diabetes and depression are global health problems with a rising prevalence, affecting 10.5 and 5% of the world population, respectively [1, 2]

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Cell Rep 27(2):491-501.e496 Okazaki A, Gameiro PA, Christodoulou D, Laviollette L, Schneider M, Chaves F, Stemmer-Rachamimov A, Yazinski SA, Lee R, Stephanopoulos G, Zou L, Iliopoulos O (2017) Glutaminase and poly(adp-ribose) polymerase inhibitors suppress pyrimidine synthesis and vhl-deficient renal cancers

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Methods The workflow of the study is presented in Fig

Sections were subsequently developed using the avidin-biotin peroxidase complex system (ABC kit, BOSTER Ltd