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GLP1R and amylin agonism in metabolic disease: complementary mechanisms and future opportunities

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The red transcript variants do not codify for any isoform

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These were all 5-HT1b agonists characterized for their ability to inhibit food consumption, but also had effects on other serotonin receptors that lead to unacceptable side effects (cardiac valvular thickening) and were voluntarily withdrawn from the market

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