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This highlights the ongoing need for patient education and provider support around managing tolerability, particularly during dose escalation phases

Wang F, Bao Y, Zhang C, Zhan L, Khan W, Siddiqua S, Ahmad S, Capanoglu E, Skalicka-Woniak K, Zou L, Simal-Gandara J

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Irbesartan, an angiotensin receptor blocker, inhibits the activation of the Hippo/YAP1/TAZ signaling pathway, decreasing c-Jun expression, which upregulates iron metabolism genes and suppresses ferroptosis