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BSO, or other drugs targeting GCLC, is a candidate drug for GCs with high ACTL6A expression

The combination of NAD+ and glutathione may support overall cellular recovery and regeneration through complementary energy and antioxidant pathways, though direct head-to-head human trials of the combination are still limited

Testing and diagnosis of NAFLD may include blood tests, imaging, and biopsy

For instance, injections carry glutathione directly to the bloodstream, while soaps can exfoliate and address uneven skin tones and pimples

528,529 Metformin, a traditional diabetes drug, upregulated the expression of mitophagy genes, such as PINK , Parkin , and Mfn2 , while at the same time effectively reducing damaged mitochondria after administration, indicating a great potential of metformin as a mitophagy activator

Based on these studies, new treatment strategies can be developed to treat ferroptosis-related diseases