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While tirzepatide is not primarily eliminated through the kidneys, the gastrointestinal effects of the medication, including potential nausea, vomiting, and diarrhea, could lead to dehydration and electrolyte imbalances that may be particularly problematic in patients with compromised kidney function

Some people may be sensitive to sugar alcohols used as sweeteners, which can cause gastric symptoms in higher amounts

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No, stick to the recommended dose

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