Type of reaction Enzyme Endogenous conjugating agent Examples of drugs metabolized by the same pathway Glucuronidation UDP- glucuronosyltransferase UDP-Glucoronic acid Chloramphenicol, morphine, paracetamol, salicylic acid, propofol fenoprofen, diazepam Sulfation Sulfotransferases sulfate Paracetamol, salbutamol Glycine/ glutamine conjugation JV-Acyl transferases Glycine Glutamine Cholic acid, salicylic acid, nicotinic acid, phenylacetic acid Glutathione conjugation Glutathione S transferases Glutathione Adriamycin, busulfan, chlorambucil, cis-platin, cyclophosphamide, ethacrynic acid Acetylation N- Acetyl transferases Acetyl-CoA Histamine, procainamide, sulfonamides, isoniazid, hydralazine Methylation Methyl transferase S-Adenosyl-L- methionine Morphine, norephedrine, nicotine, histamine, isoprenaline, propylthiouracil Uridine diphosphate-glucuronosyltransferases Glucuronidation is the most common and the most important conjugation reaction
Whats for lunch
In this work, we test a deep generative latent diffusion model (LDM) for the downscaling task, conditioned with low-resolution predictors and high-resolution static data
Le Glutathione est une petite molcule compose de trois acides amins : la cystine, lacide glutamique et la glycine
Your digestive health matters too: a healthy gut microbiome and anti-inflammatory diet support the other pathway your body uses to break down histamine
It specifically encourages the production of Type I and Type III collagen, which are vital for making skin strong yet flexible
