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Mutations in NNT encoding nicotinamide nucleotide transhydrogenase cause familial glucocorticoid deficiency

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Another BA receptor, Takeda G protein-coupled receptor 5 (TGR5), has also been associated with anti-depressive symptoms, as TGR5 knockout mice exhibit anxiety and depression-like behaviors 55

N Engl J Med 356:26842692 Pedersen LH, Henriksen TB, Vestergaard M, Olsen J, Bech BH (2009) Selective serotonin reuptake inhibitors in pregnancy and congenital malformations: population based cohort study