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507 Nicorandil could inhibit mitochondrial translocation of ACSL4 and ferroptosis

95% CI 0.03 to 0.03

Nakanishi H, Kurosaki M, Tsuchiya K, et al

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Tirzepatide adds a second mechanism: it also activates the GIP (glucose-dependent insulinotropic polypeptide) receptor, the original incretin identified in the 1970s