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"Making efforts to stay hydrated may help offset some of the unpleasant oral symptoms." Another theory, based on recent studies in the journal Cureus, is that patients may experience a condition called dysaesthesia, Imaeda said, or a burning, tingling feeling "that can happen anywhere on the skin." The Cleveland Clinic defines the condition as a burning, crawling, piercing or electric sensation

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Initial assessment should include a detailed history characterizing the joint symptoms: onset relative to medication initiation, location and pattern of joint involvement, severity and functional impact, aggravating and relieving factors, and any associated symptoms such as swelling, redness, or morning stiffness

Given that IGF1 and cognate receptor are expressed in germ cells, LCs and Sertoli cells [49], intratesticular IGF1 could regulate various aspects of testicular function in both autocrine and paracrine manners

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A balanced approach is optimal for sustainable transformation