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Results Glutamine was a more potent GLP-1 secretagogue than glucose or other amino acids, increasing GLP-1 release 7.10.7-fold ( n =19) at 10 mmol/l, with an estimated median effective concentration of between 0.1 and 1 mmol/l

Alcohol considerations Alcohol interacts with semaglutide in ways that affect both efficacy and side effects

State of play: GLP-1 drugs, which include brand-name products such as Ozempic and Wegovy, are leaving a trail of disruption throughout the economy

Activation of these receptors may modulate dopamine signaling, potentially reducing alcohol's rewarding properties, though the exact mechanisms in humans remain under investigation

Recessive SLC19A2 mutations are a cause of neonatal diabetes mellitus in thiamine-responsive megaloblastic anaemia