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RT-PCR in mice Tissues were stored in RnaLater (Ambion) or directly transferred to TRIzol (Invitrogen)
Nasal mucosal aminopeptidases and endopeptidases create a presystemic degradation barrier that is distinct from and often worse than intestinal first-pass metabolism for many peptide sequences
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Taken together, these data indicate that SFN is protective in animal models of diabetic nephropathy, and its effect is mediated by activation of NRF2
The results were highly illuminating and fundamentally shaped how practitioners approach carnitine supplementation today
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