Multi-Species Use: Can be used in dogs, cats, horses, and livestock, making it a flexible treatment option across different animal types
doi:10.1056/NEJMoa2206038 Sikiric P, et al
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These include specific disease or diagnoses, genetic variants in drug metabolizing enzymes involved in busulfan metabolism, and drug interactions including enzyme inducers or inhibitors ( In summary, this work reinforces the clinical utility for a Bayesian-based, model-informed precision platform and TDM of busulfan over historical methods for achievement of cAUC target
Formally, TRXR can be described as an oxidoreductase that relies on NADPH and FAD to reduce TRX-S2
Nat Rev Dis Primers 6(1):123 [DOI] [PubMed] [Google Scholar] De Sanctis V, Soliman AT, Canatan D, Yassin MA, Daar S, Elsedfy H, Di Maio S, Raiola G, Corrons J-LV, Kattamis C (2019) Thyroid disorders in homozygous -thalassemia: current knowledge, emerging issues and open problems
