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Following OA induction, the rabbits were randomly divided into four groups with 8 subjects, each receiving a different weekly intra-articular treatment starting four weeks after the first collagenase injection

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GHK-Cu (glycyl-L-histidyl-L-lysine copper, also called copper tripeptide-1) is a naturally occurring tripeptide-copper complex first isolated from human plasma in 1973 by Dr

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This is a mechanistically appealing strategy with strong preclinical support