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Incretin-based therapy for diabetes prevention in patients with obesity In agreement with what has been previously shown for any weight-lowering lifestyle intervention and medication, regardless of their mechanism of action 18 , incretin-based AOM have been associated with amelioration of glucose metabolism and T2D prevention (Fig

How GLP-1s Work Mechanism: Mimic or enhance incretin hormones (GLP-1) to reduce appetite , slow gastric emptying , improve insulin secretion , and lower blood glucose

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This means very small amounts may have strong biological effects