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Beginners should not use it without medical screening, lab review, and ongoing monitoring

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If you suspect tirzepatide may be causing sleep disturbances, you can report this as a suspected adverse reaction via the MHRA Yellow Card Scheme (yellowcard.mhra.gov.uk or the Yellow Card app)

Studies have noted higher rates of gastrointestinal disorders, hypotension, syncope, kidney stones (nephrolithiasis), interstitial nephritis, and drug-induced pancreatitis