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For description of ARNA response to intrapelvic injection of GLP-1 (3 M in saline, Enzo Life science, Farmingdale, NY), ARNA was expressed as a percent changes from the baseline value and also normalized to maximal ARNA induced by intrapelvic injection of capsaicin (100 M in 5% ethanol and 95% saline, Sigma, Saint Louis, MO) thus expressed as a percent of ARNAmax as shown previously [24, 26, 34]

Where indicated, cells were treated with 2-h pulses of 1 M epirubicin, 5 M 5FU, twice a week or irradiated with 2 Gy (once a week using an Xstrahl CIX2 or RPS CellRad RSM-009 irradiators)

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This can increase the production of inflammatory substances, which may lead to breakouts

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