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Its broad healing profile spans gut, tendon, muscle, and beyond

SGLT2 is expressed nearly exclusively in the apical membranes of epithelial cells of the proximal tubule of the kidney and has been shown to be responsible for approximately 90% of the renal glucose reabsorption (see Figure below)

While tests such as CVLT, BNT, and UPSIT offer valuable diagnostic insight, particularly in early or prodromal stages, their limited dynamic range and susceptibility to ceiling or floor effects constrain their utility as response biomarkers