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Beta-blockers used to manage Graves' symptoms can promote weight gain, while aggressive calorie restriction may worsen thyroid-related metabolic dysfunction

At later stages in the drug development process, the FDA intends to reform institutional review board processes for multisite studies, make it easier to write and amend clinical trial protocols, and explore allowing larger incentives for patients who participate in clinical trials and their physicians

The blood pressure-lowering effect appears to be driven primarily by weight loss (patients in the STEP trials lost 10-15% of body weight), though improvements in insulin sensitivity and vascular function may also contribute

Those who take Prozac with cocaine will have higher concentrations of cocaine in the body at the end of the day

If the buzz feels less compelling, the pull to keep drinking can fade

Both medications contain the same compound