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Conversely, in a cardiovascular outcomes study of participants with overweight or obesity and no diabetes (neither Type 1 nor Type 2) called SELECT, the benefits of semaglutide in lowering adverse cardiovascular events emerged early in the trial before significant weight loss had time to occur. Vest, who was not involved in this study, leads a metabolic heart failure clinic at the Cleveland Clinic in Cleveland, Ohio, where she is the section head of heart failure and transplant cardiology and the George M

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This is relevant not only for side effect management but for fertility: dutasteride is contraindicated in women of childbearing age and in men who may be trying to conceive, given its effects on DHT-dependent fetal development