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All experimental data were calculated as mean SD

The formation and maintenance of collagen rely on growth hormone

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Clinical trials such as the STEP 1 study demonstrated significant weight reductiontypically 14.9% of body weight over 68 weeks compared with 2.4% with placeboalongside improvements in cardiovascular risk factors

All the online tools and databases used are mentioned in Supplementary Table S2 (Supplementary File 2)

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