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However, it is rendered ineffective when evaluating possible toxicity due to multiple ingestions over time, when time of ingestion is unknown, or when altered metabolism occurs

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10.1056/NEJMoa0911101 [DOI] [PubMed] [Google Scholar] 2.Tajar A, Forti G, ONeill TW, Lee DM, Silman AJ, Finn JD, Bartfai G, Boonen S, Casanueva FF, Giwercman A, Han TS, Kula K, Labrie F, et al

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The combination appears to affect fat distribution patterns, potentially reducing visceral fat more effectively than peripheral fat stores