Chronic inflammation, hormonal disruption, social stigma, and altered brain chemistry all play interconnected roles
el Azzouzi H, Leptidis S, Dirkx E, Hoeks J, van Bree B, Brand K, McClellan EA, Poels E, Sluimer JC, van den Hoogenhof MM, Armand AS, Yin X, Langley S, Bourajjaj M, Olieslagers S, Krishnan J, Vooijs M, Kurihara H, Stubbs A, Pinto YM, Krek W, Mayr M, da Costa Martins PA, Schrauwen P, De Windt LJ (2013) The hypoxia-inducible microRNA cluster miR-199a214 targets myocardial PPAR and impairs mitochondrial fatty acid oxidation
It requires years of pharmaceutical engineering and is not analogous to putting berberine on the skin
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