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Cations, which are attracted to the negatively charged proteoglycans, create a strong osmotic gradient that draws water molecules into the NP [2]

Table 1 a GA1 glutaric acidemia type 1, MMA methylmalonic acidemia, PA propionic acidemia b IV indicates a patient whom was taken off oral carnitine (prior chronic PO dose is listed) and instead was on intravenous carnitine replacement for 10 days prior to sampling as a result of illness and inpatient hospitalization c Antibiotic treatments within 30 days of sampling are listed

Fibre has various benefits, depending on the type, but all fibre is good fibre, and we need a variety of sources to get the full spectrum of benefits

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Safdie FM, Dorff T, Quinn D, Fontana L, Wei M, Lee C et al

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