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Specifically, the Food and Drug Administration Adverse Event Reporting System (FAERS) was searched for ADE reports between drugs suggested by the in silico modelling and outcomes of interest in order to investigate real-world evidence of the potential ADE and increased risk of COPD [19]

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The controlled release of DNAzymes, the maximal cytocompatibility, and significantly improved BBB permeability suggest that our DNZ-NLPs offer a promising formulation for delivering all types of oligonucleotides to the brain for neurodegenerative disease treatments

301 , C862C871 (2011)

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