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The secretion of adiponectin from adipose tissue enhanced by both incretins elicits a signal akin to a fasting state in hepatocytes through the cAMP/pAMPK pathway

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Los estudios de seguridad a largo plazo, como el ensayo SUSTAIN-6 con semaglutida, han documentado perfiles de seguridad aceptables durante perodos de 2 aos o ms