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Parkin loss leads to PARIS-dependent declines in mitochondrial mass and respiration

H&E staining results further confirmed that the aortic wall thickness of mice treated with FOXO4-DRI was significantly thinner, and ultrasound examination results showed that the PWV of the aorta was slowed down after FOXO4-DRI treatment, indicating better vascular elasticity and significantly improved vascular function compared to the control group (Figures 2D,E)

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As a cosmetic chemist, Ive learned that the most powerful ingredients are rarely trendy. Theyre usually the molecules our bodies already know how to use